Current anti-diabetes mechanisms and clinical trials using Morus alba L.
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چکیده
منابع مشابه
Anti-inflammatory and anti-cancer activity of mulberry (Morus alba L.) root bark
BACKGROUND Root bark of mulberry (Morus alba L.) has been used in herbal medicine as anti-phlogistic, liver protective, kidney protective, hypotensive, diuretic, anti-cough and analgesic agent. However, the anti-cancer activity and the potential anti-cancer mechanisms of mulberry root bark have not been elucidated. We performed in vitro study to investigate whether mulberry root bark extract (M...
متن کاملExtraction, purification and anti-fatigue activity of γ-aminobutyric acid from mulberry (Morus alba L.) leaves
Mulberry (Morus alba L.) is a tree species of Moraceae widely distributed in Southern China. In the present study, the white crystal of γ-aminobutyric acid (GABA) was purified from mulberry leaves, and its bioactivity was also investigated. The main results were as follows: first, the crude GABA was extracted from mulberry leaves by using biochemical methods. Then, the crude was purified by chr...
متن کاملAnti-dopaminergic effect of the methanolic extract of Morus alba L. leaves
OBJECTIVE To evaluate the effect of methanolic extract of Morus alba L. leaves on dopaminergic function. MATERIALS AND METHODS The effect of the methanolic extract of Morus alba L. leaves was evaluated on haloperidol and metoclopramide induced catalepsy, foot shock-induced aggression, amphetamine-induced stereotyped behavior and phenobarbitone induced sleeping in mice. In each of these tests,...
متن کاملPreventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats
The mulberry plant (Morus alba L.) contains abundant anthocyanins (ANCs), which are natural antioxidants. The aim of this study was to determine the ANC composition of Thai Morus alba L. fruits and to assess the effect of an ANC extract on blood glucose and insulin levels in male leptin receptor-deficient Zucker diabetic fatty (ZDF) rats. The major components of the ANC extract were identified ...
متن کاملAntidiabetic and Antioxidant Effects and Phytochemicals of Mulberry Fruit (Morus alba L.) Polyphenol Enhanced Extract
The antidiabetic and antioxidant activities of the ethyl acetate-soluble extract (MFE) of mulberry fruit (Morus alba L.) were investigated. In vitro, MFE showed potent α-glucosidase inhibitory activity and radical-scavenging activities against DPPH and superoxide anion radicals. In vivo, MFE could significantly decrease fasting blood glucose (FBG) and glycosylated serum protein (GSP), and incre...
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ژورنال
عنوان ژورنال: Journal of Traditional Chinese Medical Sciences
سال: 2016
ISSN: 2095-7548
DOI: 10.1016/j.jtcms.2016.04.001